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Lung Cancer Research Programs

2007

  • Lung cancer is the leading cause of death from cancer worldwide. In the United States alone, 160,000 people are expected to die from lung cancer in 2007. These high lung cancer mortality rates...

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  • Tuberous sclerosis is a tumor predisposition syndrome that is due to mutations in the TSC1 and TSC2 genes. Tuberous sclerosis patients often develop benign tumors in their lungs. No one has...

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  • Cancer is caused by the accumulation of somatic mutations and / or chromosomal rearrangements in key proteins that have a central role in cellular homeostasis. Such proteins participate in a...

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  • Lung cancer is the leading cause of cancer deaths in the United States. Over 80,000 new lung cancers were diagnosed in United States among women in 2004, and 68,500 of those women will die from...
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  • Many genetic alterations are known to occur in lung cells that become cancerous. One of the most prevalent of these is a mutation in a gene called Kras. Despite years of investigation, it is...

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  • Recently, scientists found mutations in some lung adenocarcinomas and bronchioalveolar carcinomas that activate a tumor promoting receptor called EGFR. We found that these mutations in EGFR...

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  • Lung cancer is the leading cause of cancer death for both men and women in the US. In 2007 alone, over 160,000 patients will succumb to lung cancer, more than the combined deaths from the breast,...

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2006

  • Bronchioalveolar carcinoma (BAC) is a subtype of non-small cell lung cancer (NSCLC), the most common form of lung cancer. The overall incidence of BAC has been controversial. Some see its...

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  • Lung cancer is a world-wide menace causing enormous suffering, misery, and death. Bronchioalveolar carcinoma (BAC) is one type of lung cancer that typically presents as a single or multiple...

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  • There is an urgent need for efficient, non-toxic biological therapies for lung cancer, particularly for advanced disease, where current therapies are often inadequate. Tumor suppressor gene...

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